Move from room to room as Isaac as you take on strange monsters, and flies around piles of poop. The game The Binding of Isaac belongs to the categories Action, Shoot Em Up and has been played 41099 times. It has a score of 84 and it has received 438 yes and 82 no. In the same categories you can find the games Galaxy Attack: Alien Shooter and Battle for the Galaxy which we think you should try.
Instructions: See instructions in the game.